1.6.1.1 Cyclic vomiting syndrome

Identification: Male patient, 12 years old, previously healthy. Clinical History: The patient presents with recurrent episodes of intense and incapacitating vomiting, lasting 24 to 48 hours, since the age of 8. The episodes occur every 4-6 weeks, without clear triggering factors. During the episodes, the patient experiences intense nausea, frequent vomiting (up to 10-15 times per hour), diffuse abdominal pain, pallor, and prostration. Between episodes, the patient is completely asymptomatic, with normal growth and development. Family History: The mother reports a history of migraine in childhood and adolescence. Complementary Exams: Complete blood count, electrolytes, liver and renal function tests are normal. Upper gastrointestinal endoscopy: no abnormalities. Brain MRI: normal. Metabolic and genetic tests: negative.