Case 520 · ICHD-3 8.1.2

8.1.2 Phosphodiesterase (PDE) inhibitor-induced headache

Origin

Synthetic

Language

English — also available in German

Contributed by

Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)

Anamnesis

Identification: A 45-year-old male patient reports an intense bilateral, pulsatile headache lasting 4 hours, which began 1 hour after using sildenafil (50 mg) for erectile dysfunction. He denies any previous history of primary headaches or chronic medication use.

Physical/Neurological Examination: Unremarkable. Blood Pressure: 120/80 mmHg.

Report this case — e.g. suspected re-identification risk.