Case 554 · ICHD-3 8.2.3.1

8.2.3.1 Paracetamol (acetaminophen)-overuse headache

Origin

Synthetic

Language

English — also available in German

Contributed by

Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)

Anamnesis

Identification: A 35-year-old female patient reports daily headaches for 3 months, with progressive worsening.

Headache History:

Headache present on ≥15 days/month, with variable characteristics (bilateral pressure or pulsatile), moderate intensity.

Regular use of paracetamol (acetaminophen) on ≥15 days/month (average of 4 tablets of 500 mg/day) for 4 months, initially for episodic headaches.

Reports some improvement in headache with reduction or discontinuation of the analgesic.

Physical/Neurological Examination: No significant findings.

Report this case — e.g. suspected re-identification risk.