Case 572 · ICHD-3 8.3.1

8.3.1 Caffeine-withdrawal headache

Origin

Synthetic

Language

English — also available in German

Contributed by

Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)

Anamnesis

Identification: A 32-year-old female patient reports a moderate intensity throbbing holocranial headache, which worsens with movement and partially improves with rest. The headache began 24 hours after the abrupt cessation of her habitual coffee consumption (approximately 400 mg of caffeine/day, equivalent to 4 cups, for 5 years). Associated symptoms include fatigue, difficulty concentrating, and irritability. The headache lasted 48 hours and resolved spontaneously after the reintroduction of caffeine.

Report this case — e.g. suspected re-identification risk.