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Top-1 (diagnosis) by model size

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0 % 25 % 50 % 75 % 100 % 100M 200M 500M 1B 2B 5B 10B 20B 50B 100B 200B 500B 1T 2T 5T 10T Parameters (log scale) NotebookLM (Gemini 3.0 Pro) Head.AI (GPT-4o + ICHD-3 knowledge base) Grok Claude Sonnet Ministral 3 14B Instruct o3-mini Qwen3-14B gpt-4.1 Gemma 3 27B IT gpt-4-turbo Gemma 3 12B IT gpt-3.5-turbo
  • Prompting
  • Retrieval-augmented
  • Verified
  • Unverified or as reported

Not shown (no size or no Top-1 (diagnosis) value): gpt-4.1 API, accessed 2025-11-10, Gradient boosting classifier Katsuki et al. 2023 model.

Datasets (none ticked = all)
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Some results come from publications or team runs on external datasets rather than a platform release; they are shown as reported and are not directly comparable with results on a different dataset. Select a dataset name for its details; * marks a note on the result itself. Results marked Platform team were produced by the people who run this platform — disclosed because the same team curates the data and verifies results.

Model Approach Dataset Top-1 (diagnosis) Share of cases in which the model's first-ranked diagnosis matches the reference ICHD-3 diagnosis exactly (e.g. 1.1 Migraine without aura). Top-3 (diagnosis) Share of cases in which the reference ICHD-3 diagnosis is among the model's three highest-ranked diagnoses. Top-1 (group) Share of cases in which the model's first-ranked diagnosis falls into the same ICHD-3 diagnostic group as the reference (e.g. any 1.x for 1.1 Migraine without aura) — a coarser, more lenient measure. Top-3 (group) Share of cases in which at least one of the model's three highest-ranked diagnoses falls into the reference ICHD-3 diagnostic group. Cohen's Kappa Cohen's κ: agreement between the model's diagnoses and the expert reference, corrected for agreement expected by chance. 1 = perfect, 0 = chance level; the study targets κ ≥ 0.8. Cost Links Submitter Date
gpt-3.5-turbo 2025-04-16
Verified Peer-reviewed publication ↗
Criteria as text 24.04 % 39.02 % 66.90 % — — — Paper — 2026-10-22
gpt-3.5-turbo 2025-04-16
Verified Peer-reviewed publication ↗
Naive prompt 33.10 % 47.04 % 80.14 % — — — Paper — 2026-10-22
gpt-3.5-turbo 2025-04-16
Verified Peer-reviewed publication ↗
Criteria as JSON 36.93 % 60.97 % 75.96 % — — — Paper — 2026-10-22
Gemma 3 12B IT google/gemma-3-12b-it
Verified Peer-reviewed publication ↗
Zero-shot 42.30 % — 83.61 % — — — Paper — 2026-10-22
gpt-4-turbo 2025-04-16
Verified Peer-reviewed publication ↗
Criteria as text 44.95 % 78.05 % 86.06 % — — — Paper — 2026-10-22
Gemma 3 12B IT google/gemma-3-12b-it
Verified Peer-reviewed publication ↗
Chain-of-thought 45.57 % 53.80 % 86.23 % — — — Paper — 2026-10-22
Gemma 3 12B IT google/gemma-3-12b-it
Verified Peer-reviewed publication ↗
ICHD-3 criteria in context 45.90 % 43.60 % 81.31 % — — — Paper — 2026-10-22
Gemma 3 12B IT google/gemma-3-12b-it
Verified Peer-reviewed publication ↗
Few-shot 47.54 % 52.80 % 86.23 % — — — Paper — 2026-10-22
Gemma 3 27B IT google/gemma-3-27b-it
Verified Peer-reviewed publication ↗
ICHD-3 criteria in context 49.18 % 58.00 % 87.87 % — — — Paper — 2026-10-22
o3-mini 2025-04-16
Verified Peer-reviewed publication ↗
Criteria as JSON 50.87 % 71.08 % 75.96 % — — — Paper — 2026-10-22
Qwen3-14B Qwen/Qwen3-14B
Verified Peer-reviewed publication ↗
Zero-shot 52.79 % 64.30 % 87.21 % — — — Paper — 2026-10-22
Gemma 3 27B IT google/gemma-3-27b-it
Verified Peer-reviewed publication ↗
Chain-of-thought 53.44 % 56.40 % 90.16 % — — — Paper — 2026-10-22
Gemma 3 27B IT google/gemma-3-27b-it
Verified Peer-reviewed publication ↗
Zero-shot 53.77 % 58.40 % 89.84 % — — — Paper — 2026-10-22
gpt-4-turbo 2025-04-16
Verified Peer-reviewed publication ↗
Criteria as JSON 55.05 % 80.14 % 86.06 % — — — Paper — 2026-10-22
gpt-4.1 2025-04-16
Verified Peer-reviewed publication ↗
Naive prompt 55.05 % 75.96 % 88.15 % — — — Paper — 2026-10-22
Gemma 3 12B IT google/gemma-3-12b-it
Verified Peer-reviewed publication ↗
RAG (ICHD-3 retrieval) 55.41 % 59.30 % 89.51 % — — — Paper — 2026-10-22
Qwen3-14B Qwen/Qwen3-14B
Verified Peer-reviewed publication ↗
RAG (ICHD-3 retrieval) 56.72 % 64.60 % 85.57 % — — — Paper — 2026-10-22
Mistral Small 3.2 24B Instruct mistralai/Mistral-Small-3.2-24B-Instruct-2506
Verified Peer-reviewed publication ↗
RAG (ICHD-3 retrieval) 57.05 % 63.50 % 86.56 % — — — Paper — 2026-10-22
Gemma 3 27B IT google/gemma-3-27b-it
Verified Peer-reviewed publication ↗
Few-shot 57.05 % 61.60 % 91.15 % — — — Paper — 2026-10-22
gpt-4-turbo 2025-04-16
Verified Peer-reviewed publication ↗
Naive prompt 57.14 % 78.05 % 86.06 % — — — Paper — 2026-10-22
gpt-4.1 2025-04-16
Verified Peer-reviewed publication ↗
Criteria as JSON 57.14 % 75.96 % 89.89 % — — — Paper — 2026-10-22
Gemma 3 27B IT google/gemma-3-27b-it
Verified Peer-reviewed publication ↗
RAG (ICHD-3 retrieval) 57.38 % 61.60 % 90.49 % — — — Paper — 2026-10-22
o3-mini 2025-04-16
Verified Peer-reviewed publication ↗
Naive prompt 58.88 % 75.96 % 80.14 % — — — Paper — 2026-10-22
gpt-4.1 2025-04-16
Verified Peer-reviewed publication ↗
Criteria as text 58.88 % 68.99 % 91.98 % — — — Paper — 2026-10-22
Mistral Small 3.2 24B Instruct mistralai/Mistral-Small-3.2-24B-Instruct-2506
Verified Peer-reviewed publication ↗
Zero-shot 59.34 % 73.50 % 89.51 % — — — Paper — 2026-10-22
Qwen3-14B Qwen/Qwen3-14B
Verified Peer-reviewed publication ↗
Few-shot 60.00 % 70.50 % 89.18 % — — — Paper — 2026-10-22
Ministral 3 14B Instruct mistralai/Ministral-3-14B-Instruct-2512
Verified Peer-reviewed publication ↗
RAG (ICHD-3 retrieval) 61.64 % 69.20 % 90.49 % — — — Paper — 2026-10-22
Qwen3-14B Qwen/Qwen3-14B
Verified Peer-reviewed publication ↗
Chain-of-thought 62.62 % 70.80 % 89.18 % — — — Paper — 2026-10-22
Mistral Small 3.2 24B Instruct mistralai/Mistral-Small-3.2-24B-Instruct-2506
Verified Peer-reviewed publication ↗
ICHD-3 criteria in context 62.95 % 71.50 % 92.46 % — — — Paper — 2026-10-22
o3-mini 2025-04-16
Verified Peer-reviewed publication ↗
Criteria as text 63.07 % 75.96 % 83.97 % — — — Paper — 2026-10-22
Mistral Small 3.2 24B Instruct mistralai/Mistral-Small-3.2-24B-Instruct-2506
Verified Peer-reviewed publication ↗
Chain-of-thought 64.59 % 72.10 % 93.44 % — — — Paper — 2026-10-22
Mistral Small 3.2 24B Instruct mistralai/Mistral-Small-3.2-24B-Instruct-2506
Verified Peer-reviewed publication ↗
Few-shot 66.23 % 77.00 % 93.11 % — — — Paper — 2026-10-22
Ministral 3 14B Instruct mistralai/Ministral-3-14B-Instruct-2512
Verified Peer-reviewed publication ↗
Chain-of-thought 67.54 % 72.80 % 92.79 % — — — Paper — 2026-10-22
Ministral 3 14B Instruct mistralai/Ministral-3-14B-Instruct-2512
Verified Peer-reviewed publication ↗
ICHD-3 criteria in context 67.87 % 79.30 % 92.46 % — — — Paper — 2026-10-22
Ministral 3 14B Instruct mistralai/Ministral-3-14B-Instruct-2512
Verified Peer-reviewed publication ↗
Zero-shot 67.87 % 78.30 % 92.13 % — — — Paper — 2026-10-22
Ministral 3 14B Instruct mistralai/Ministral-3-14B-Instruct-2512
Verified Peer-reviewed publication ↗
Few-shot 69.18 % 77.20 % 93.44 % — — — Paper — 2026-10-22
Claude Sonnet 4.0
Peer-reviewed publication ↗
Chatbot default 74.30 % — — — — — Paper — 2026-10-22
Gemini 2.5
Peer-reviewed publication ↗
Chatbot default 77.10 % — — — — — Paper — 2026-10-22
Grok 3.0
Peer-reviewed publication ↗
Chatbot default 80.30 % — — — — — Paper — 2026-10-22
Head.AI (GPT-4o + ICHD-3 knowledge base) GPT-4o, 2025
Peer-reviewed publication ↗
ICHD-3 knowledge in prompt 89.50 % — — — — — Paper — 2026-10-22
NotebookLM (Gemini 3.0 Pro) accessed 2026-02
Peer-reviewed publication ↗
NotebookLM over ICHD-3 + guidelines 100.00 % — — — 1.000 — Paper — 2026-10-22
Gradient boosting classifier Katsuki et al. 2023 model
Peer-reviewed publication ↗
Supervised ML (questionnaire features) — — 84.21 % — 0.460 — Paper — 2026-10-22
gpt-4.1 API, accessed 2025-11-10
Peer-reviewed publication ↗
Zero-shot (structured questionnaire) — — 67.99 % — 0.260 — Paper — 2026-10-22

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