Case 152 · ICHD-3 13.2.1
13.2.1 Glossopharyngeal neuralgia
- Origin
- Synthetic
- Language
- English — also available in German
- Contributed by
- Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)
Anamnesis
Identification: Male patient, 62 years old, with episodes of oropharyngeal pain for 8 months.
History of Present Illness:
Pain:
Location: Left base of the tongue, tonsillar region, and ipsilateral ear (referred pain)
Characteristic:
Stabbing paroxysms (1-30 seconds)
Excruciating intensity (10/10)
Frequency: 5-20 episodes/day
Specific triggers:
Swallowing (especially cold liquids)
Coughing or yawning
Palpation of the tonsillar region (trigger area)
Associated symptoms:
Bradycardia and syncope in 20% of episodes (vagal reflex)
Hypersalivation during paroxysms
Interictal periods:
Completely asymptomatic
Normal neurological examination
Physical/Neurological Examination:
Oropharyngeal assessment:
Hyperesthesia in the left tonsillar pillars
Exaggerated ipsilateral gag reflex
Provocative tests:
Touching the tonsil with a tongue depressor → reproduction of the painful crisis
Cardiological assessment:
Sinus pauses documented during episodes (24-hour Holter)
Complementary Exams:
3T MRI (FIESTA):
Posteroinferior cerebellar artery compressing the glossopharyngeal nerve
Absence of expansive lesions
Neck CT Angiography:
Anomalous course of the vertebral artery
Electrophysiology:
Glossopharyngeal nerve anesthetic block (lidocaine 2%) → immediate relief
Report this case — e.g. suspected re-identification risk.