Case 164 · ICHD-3 13.6
13.6 Painful optic neuritis
- Origin
- Synthetic
- Language
- English — also available in German
- Contributed by
- Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)
Anamnesis
Identification: Female patient, 28 years old, presenting with orbital pain and acute visual loss for 5 days.
History of Present Illness: Ocular Symptoms: Pain: Location: Deep retro-orbital (left) Characteristic: Constant (6-8/10 VAS) Exacerbation with eye movements (9/10) Worsens at night Visual Deficit: Progressive low acuity (20/200) Central scotoma Dyschromatopsia for red Associated Symptoms: Uhthoff's phenomenon (worsens with increased body temperature) Phosphenes during eye movements Relevant History: Previous episode of limb paresthesias (2 years ago, not investigated)
Physical/Neurological Examination: Ophthalmological Evaluation (left eye): Pupil: Relative afferent pupillary defect (RAPD+) Fundoscopy: Edematous optic disc (papillitis) Peripapillary hemorrhages Visual field: Centrocecal scotoma Ocular Motricity Examination: Pain on forced abduction (Kennedy's sign) General Neurological Examination: No other focal deficits
Complementary Exams: Brain and Orbit MRI (with contrast): Increased signal and enhancement in the left optic nerve 3 periventricular lesions suggestive of demyelination Visual Evoked Potentials: Prolonged P100 latency (135ms) CSF: Positive IgG oligoclonal bands Increased IgG index
Report this case — e.g. suspected re-identification risk.