Case 382 · ICHD-3 6.6.1
6.6.1 Headache attributed to cerebral venous thrombosis (CVT)
- Origin
- Synthetic
- Language
- English — also available in German
- Contributed by
- Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)
Anamnesis
Identification: Female patient, 28 years old, university student
History of Present Illness: Reports a holocranial headache of moderate to severe intensity (7/10 on the visual analog scale) for 10 days, with progressive worsening. Describes the pain as constant pressure, aggravated by the Valsalva maneuver and in the supine position. Associated with the headache, she presents with nausea, vomiting, and photophobia. Denies any previous history of similar headaches.
Relevant History:
Use of combined oral contraceptive for 3 years
History of migraine without aura since adolescence (1-2 episodes/month)
Smoking (5 cigarettes/day)
Physical Examination:
BP: 130/85 mmHg
HR: 88 bpm
Febrile: 37.8°C
Neurological: bilateral papilledema, mild neck stiffness
No motor or sensory deficits
Complementary Exams:
Cranial CT: empty delta sign
MRI + venography: thrombosis of the superior sagittal sinus
CSF: protein 65 mg/dL, normal glucose, 15 leukocytes/mm3
Report this case — e.g. suspected re-identification risk.