Case 42 · ICHD-3 1.4.4
1.4.4 Migraine aura-triggered seizure
- Origin
- Synthetic
- Language
- English — also available in German
- Contributed by
- Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)
Anamnesis
Clinical History: The patient reports a history of migraine with aura since adolescence, characterized by visual symptoms (scintillating scotomas) followed by unilateral pulsatile headache, nausea, and photophobia. In the past 6 months, she has experienced episodes of migraine aura without headache, lasting 20 to 30 minutes. On two occasions, immediately following the aura, she developed a generalized tonic-clonic seizure lasting approximately 1 minute, followed by postictal confusion and drowsiness. There is no history of fever, head trauma, or illicit substance use. Physical and Neurological Examination: General physical examination: unremarkable. Neurological examination: normal in the interictal period. Additional Investigation: Cranial magnetic resonance imaging: normal. Electroencephalogram (EEG): epileptiform discharges in the left occipital region, consistent with epileptogenic activity.
Report this case — e.g. suspected re-identification risk.