headache.bench

Origin: Synthetic
Language: English — also available in German
Contributed by: Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)

Anamnesis

Identification: Sex/Age: Female, 45 years

History: Prolactin-secreting pituitary macroadenoma under treatment with cabergoline for 3 years

Medications: Cabergoline 0.5mg twice a week

Family history: Negative for endocrine diseases

History of Present Illness (HPI): Main symptom: Sudden and explosive headache for 6 hours

Characteristics:

Onset: Abrupt, during light physical activity

Location: Bilateral frontal and retro-orbital

Intensity: 10/10, described as "the worst pain of life"

Associated symptoms:

Nausea and vomiting

Sudden visual loss

Progressive drowsiness

Physical/Neurological Examination: General: Tachycardia (HR 110 bpm), normotensive

Neurological:

Decreased visual acuity (20/200 bilateral)

Bitemporal visual field defect

Complete right oculomotor nerve palsy

Glasgow Coma Scale: 13 (moderate confusion)

Complementary Exams: MRI of the Sella Turcica:

Pituitary macroadenoma of 2.5cm with T1 hyperintense area (blood)

Suprasellar extension with compression of the optic chiasm

Laboratory:

Hypocortisolemia (8am cortisol: 2.1 μg/dL)

Hyponatremia (Na+ 128 mEq/L)

Prolactin: 350 ng/mL (paradoxical increase)

Report this case — e.g. suspected re-identification risk.