Case 44 · ICHD-3 1.4.4
1.4.4 Migraine aura-triggered seizure
- Origin
- Synthetic
- Language
- English — also available in German
- Contributed by
- Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)
Anamnesis
Identification: Female patient, 32 years old, engineer.
Clinical History:
The patient reports a history of migraine with aura since adolescence, characterized by visual symptoms (scintillating scotomas) followed by unilateral pulsatile headache, photophobia, and phonophobia. In the past 6 months, she has experienced episodes of migraine aura without associated headache, lasting 20 to 30 minutes. Two weeks ago, during an aura episode, the patient experienced, for the first time, a generalized tonic-clonic seizure lasting approximately 2 minutes, accompanied by lateral tongue biting and urinary incontinence. After the seizure, she reported mental confusion and drowsiness for about 30 minutes.
Physical and Neurological Examination:
On examination, the patient was conscious, oriented, and without focal neurological deficits. Fundoscopy showed no abnormalities. Blood pressure and vital signs were within normal limits.
Complementary Exams:
Cranial Magnetic Resonance Imaging: No structural lesions or signs of vascular malformations.
Electroencephalogram (EEG): Epileptiform discharges in the left occipital region, compatible with cortical irritative activity.
Cerebral MR Angiography: No evidence of vascular anomalies.
Report this case — e.g. suspected re-identification risk.