Case 448 · ICHD-3 7.1.2
7.1.2 Headache attributed to intracranial hypertension secondary to metabolic, toxic or hormonal cause
- Origin
- Synthetic
- Language
- English — also available in German
- Contributed by
- Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)
Anamnesis
Identification: Sex/Age: Female, 28 years History: Use of levothyroxine for primary hypothyroidism (diagnosed 3 years ago) Current Medication: Levothyroxine 75 mcg/day (last dose adjusted 2 months ago) Family History: Non-contributory History of Present Illness (HPI): Main symptom: Daily headache for 3 weeks Characteristics: Location: Bifrontal Character: Pulsatile Intensity: 7/10 Aggravation: Morning and with Valsalva maneuvers Improvement: Partial with common analgesics Associated symptoms: Occasional nausea Transient blurred vision Bilateral pulsatile tinnitus Relevant factor: Abrupt discontinuation of levothyroxine 1 month ago on her own Physical/Neurological Examination: General: Obesity grade I (BMI 31) Neurological: Bilateral papilledema (Frisen grade II) Bilateral sixth cranial nerve palsy Remaining examination normal Meningeal signs: Absent Complementary Exams: Brain MRI: Normal ventricles, no expansive lesions Lumbar puncture: ICP = 32 cm H₂O (normal <25) Clear CSF, no pleocytosis Normal proteins and glucose Laboratory: TSH = 18 mIU/L (0.4-4.0) Free T4 = 0.5 ng/dL (0.8-1.8) Other tests normal
Report this case — e.g. suspected re-identification risk.