headache.bench

Origin: Synthetic
Language: English — also available in German
Contributed by: Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)

Anamnesis

Identification: Sex/Age: Female, 8 years old

History: Genetically confirmed Down syndrome (trisomy 21)

Previous History: Global delay in neuropsychomotor development, hypothyroidism under treatment

History of Present Illness (HPI): Main symptom: Daily headache for 3 weeks

Characteristics of the pain:

Location: Bifrontal

Character: Continuous pressure

Intensity: 6-7/10

Worsens: In the morning and when lying down

Associated symptoms:

Occasional vomiting (more frequent in the morning)

Progressive diplopia

Increased irritability

Physical/Neurological Examination:

General: Short stature, phenotype compatible with trisomy 21

Neurological:

Bilateral papilledema on fundoscopic examination

Bilateral sixth cranial nerve palsy

Normal deep tendon reflexes

No motor or sensory deficits

Complementary Exams:

Magnetic Resonance Imaging of the Brain:

Collapsed ventricles

Absence of expansive lesions

Partial empty sella

Lumbar Puncture:

Opening pressure: 32 cmH2O

Clear cerebrospinal fluid, no cytochemical alterations

Genetic: Previous confirmation of trisomy 21

Report this case — e.g. suspected re-identification risk.