headache.bench

Origin: Synthetic
Language: English — also available in German
Contributed by: Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)

Anamnesis

Identification: Sex/Age: Female, 35 years

History: History of infertility (under investigation), no other known comorbidities

Medication: No regular medication

History of Present Illness (HPI): Main symptom: Constant frontal headache for 3 weeks

Pain characteristics:

Location: Bilateral frontal and retro-orbital

Character: Continuous pressure

Intensity: 7/10

Course: Progressive, unresponsive to NSAIDs

Associated symptoms:

Blurred vision

Extreme fatigue

Secondary amenorrhea (3 months)

Polyuria/polydipsia (5L/day)

Physical/Neurological Examination: General: Hypoactive, pale and dry skin

Neurological:

Bitemporal hemianopsia

Partial paresis of the right third cranial nerve

Decreased deep tendon reflexes

Other findings:

Blood pressure: 90/60 mmHg

Heart rate: 58 bpm

Complementary Exams: Magnetic Resonance Imaging of the Sella Turcica:

Diffuse enlargement of the pituitary gland (12mm)

Homogeneous enhancement with contrast

No chiasmatic compression

Laboratory:

Serum cortisol: 3.2 μg/dL (low)

TSH: 0.8 mIU/L with free T4: 0.5 ng/dL (low)

Prolactin: normal

IGF-1: reduced

Report this case — e.g. suspected re-identification risk.