Case 486 · ICHD-3 7.4
7.4 Headache attributed to intracranial neoplasia
- Origin
- Synthetic
- Language
- English — also available in German
- Contributed by
- Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)
Anamnesis
Identification: Sex/Age: Female, 42 years
History: None relevant
Medication: Occasional use of NSAIDs for headache
Family history: Mother with breast cancer
History of Present Illness (HPI): Main symptom: Chronic progressive headache for 3 months
Characteristics:
Location: Holocranial
Character: Constant pressure
Intensity: 6/10, progressively worsening
Timing: More intense upon awakening
Aggravating factors: Change of position, physical exertion
Relieving factors: No analgesic effective
Associated symptoms:
Occasional nausea and vomiting
Progressive visual blurring
Loss of balance
Mild mental confusion
Physical/Neurological Examination: General: General condition preserved
Neurological:
Gait ataxia
Bilateral horizontal nystagmus
Bilateral papilledema
Symmetrical brisk deep tendon reflexes
Complementary Exams: Brain MRI: Expansive lesion of 4 cm in the fourth ventricle with secondary hydrocephalus
Chest/Abdomen CT: No metastases
Biopsy: Medulloblastoma (WHO grade IV)
Lumbar puncture: Opening pressure >25 cmH2O (not initially performed due to risk of herniation)
Report this case — e.g. suspected re-identification risk.