Case 490 · ICHD-3 7.4.2
7.4.2 Headache attributed to carcinomatous meningitis
- Origin
- Synthetic
- Language
- English — also available in German
- Contributed by
- Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)
Anamnesis
Identification:
Sex/Age: Female, 58 years
History: Invasive ductal carcinoma of the breast (diagnosed 2 years ago, with known bone metastases)
Current Medication: Common analgesics, palliative chemotherapy
History of Present Illness (HPI):
Progressive headache for 3 weeks
Characteristics:
Diffuse
Constant
Intensity 7-8/10
Progressive worsening
Unresponsive to usual analgesics
Associated symptoms:
Nausea
Vomiting
Recent diplopia
Mild mental confusion
Physical/Neurological Examination:
Bilateral sixth cranial nerve palsy
Moderate neck stiffness
Positive meningeal signs
Mildly impaired cognitive function
Complementary Exams:
Brain MRI: Diffuse meningeal enhancement
CSF:
Increased intracranial pressure
Low glucose levels
Elevated protein levels
Positive cytology for neoplastic cells
Elevated tumor markers
Report this case — e.g. suspected re-identification risk.