Case 574 · ICHD-3 8.3.2
8.3.2 Opioid-withdrawal headache
- Origin
- Synthetic
- Language
- English — also available in German
- Contributed by
- Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)
Anamnesis
Identification: Female patient, 45 years old, with a history of chronic migraine (ICHD-3 code 1.3) for 10 years. Reports daily use of tramadol (100 mg/day) for 6 months for headache relief, without regular medical supervision. Current History: 3 weeks ago, she abruptly discontinued the opioid on her own. Since then, she has experienced daily, bilateral headaches, either pressing or pulsatile, of moderate to severe intensity, worsening rapidly after discontinuation. The headache is temporarily relieved with the reintroduction of the opioid but returns within 24 hours. Denies other symptoms (nausea, photophobia, or phonophobia beyond the usual). Complementary Exams: Brain MRI without alterations.
Report this case — e.g. suspected re-identification risk.