Case 588 · ICHD-3 9.1.2.1

9.1.2.1 Headache attributed to viral meningitis

Origin

Synthetic

Language

English — also available in German

Contributed by

Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)

Anamnesis

History: A 28-year-old male patient, previously healthy, presents with a diffuse and intense headache for 2 days, associated with fever (38.5°C), photophobia, and neck stiffness. He reports a sudden onset of symptoms following a flu-like illness (rhinorrhea and myalgia). He denies any history of trauma or immunosuppression.

Physical Examination: Positive neck stiffness (Brudzinski's sign), without focal neurological deficits.

Complementary Exams:

CSF: Leukocytosis (120 cells/mm³, lymphocytic predominance), elevated protein (80 mg/dL), normal glucose. PCR negative for bacteria.

CSF PCR: Positive for enterovirus.

Report this case — e.g. suspected re-identification risk.