Case 590 · ICHD-3 9.1.2.2

9.1.2.2 Headache attributed to viral encephalitis

Origin

Synthetic

Language

English — also available in German

Contributed by

Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)

Anamnesis

History: A 32-year-old male patient, previously healthy, presents with a diffuse, progressive, and pulsatile headache for 5 days, associated with fever (38.5°C), mental confusion, and photophobia. He reports a history of gastrointestinal viral infection the previous week. Neurological examination reveals neck stiffness and psychomotor slowing. Complementary Exams: CSF: Lymphocytic pleocytosis (80 cells/mm³), elevated protein (80 mg/dL), normal glucose. Brain MRI: Bilateral medial temporal T2 hyperintensity. PCR for HSV-1 in CSF: Positive.

Report this case — e.g. suspected re-identification risk.