Case 610 · ICHD-3 7.4.1
7.4.1 Headache attributed to intracranial neoplasm
- Origin
- Synthetic
- Language
- English — also available in German
- Contributed by
- Imported case — HeadAI synthetic vignettes (de Andrade JBC, da Silva Costa TB, Vasconcelos JL, Lopes TLM, Balsells MD, Cristofolini VL, Querobin SO, Filho FMR. Validation of an AI-based platform for structured diagnosis of headache disorders using ICHD-3 criteria. BMC Neurology 25, 489 (2025). doi:10.1186/s12883-025-04473-1. Dataset: Andrade J. Head.AI Platform. Mendeley Data, V2 (2025). doi:10.17632/4fms6cw2s5.2)
Anamnesis
Identification:
Sex/Age: Male, 58 years
Medical History: Controlled hypertension, smoking (30 pack-years)
Family History: No cases of neoplasms or chronic headaches
History of Present Illness (HPI):
Progressive headache for 8 weeks
Characteristics:
Location: Bilateral frontal and occipital
Character: Constant pressure
Intensity: 7/10 (VAS)
Worsens at night and upon waking
Aggravated by Valsalva maneuvers
Associated Symptoms:
Morning nausea
Progressive blurred vision
Unintentional weight loss of 5 kg in the last month
Physical/Neurological Examination:
Right central facial paresis
Bilateral papilledema
Extensor plantar reflex on the right
Ataxic gait
Complementary Exams:
Cranial MRI: Heterogeneous expansive lesion in the left frontal lobe (3.5 cm) with mass effect and vasogenic edema
Biopsy: Glioblastoma multiforme (WHO grade IV)
Report this case — e.g. suspected re-identification risk.